I strap my tripod to the outside and pack the following in the bag
hard shell gore-tex jacket
GPS +extra batteries
dark angel kit
4 game bags
I was just referring to Kuiu not coming with a bladder, can’t speak for the other. As to the problems you mentioned I’m unaware of any. I can speak for mine and many others that I have spent a lot of time in the woods with. No problem with any of them. Only bag I’d haul 2 front elk quarters or an entire quartered mule deer in one trip. The suspension system is awesome.
I have the Badlands Clutch pack. It's just slightly bigger than most day packs but can pack out over 100 lbs of meat in one go. It is very sturdy and very comfortable. My cousin has used the Eberlestock X2 pack for years and that has been a great pack for him. It has hauled thousands of pounds of elk and mule deer out of the Utah mountains over the years.
My Clutch has what they call a "beaver tail" pack on the outside. This outter pack is removable (making it more like a 2200) and is lashed to the main pack by 7 straps (2 on the botton, 2 on the top, and 3 across the middle). You can put your meat in between the main pack and the outter pack and then strap it all down nice and tight. The 2200 uses a similar strapping system with a soft "meat shelf" on the bottom minus the outter pack. Basically the meat is secured to the outside of the pack. If you don't have much in the main compartment or don't mind whatever is in there getting a little bloody, you can load a quarter in there too. Just do a quick search for the Clutch and 2200 to see reviews and images of each and how they load.
I'm sure it can carry more than I can down the mountain.
Large for a day bag but they can compress down well.
Most of the bags mentioned have a place for hydration bladders but aren't included.
OutdoorGearlab is a good place to see reviews on bladders.
Another vote for the Kuiu Icon systems. Very impressed with the little 1850 pack. I did 28miles with 40 lbs of backpacking gear (mine plus wife’s plus 4yrolds) this summer, easy packout head and horns this fall. Buddy hauled out 2 moose in AK with his larger Kuiu pack, same frame on both pack, just different bags. I can’t think of anything I would change, will probably get some backcountry ski trips in with it this winter, lots of options for one pack